Lynette battles cancer; the newlywed – but unhappy – Gabrielle starts an affair with her ex-husband Carlos; Susan and Mike enjoy life as a married couple and learn that they are expecting a child; Bree fakes a pregnancy and plans to raise her teenage daughter's illegitimate child as her own; and Edie schemes to hold on to her new love, Carlos.A gay couple from Chicago – Lee Mc Dermott (Kevin Rahm) and Bob Hunter (Tuc Watkins) – become residents of Wisteria Lane.Gabrielle struggles with Carlos' blindness, two young daughters, and a financial crisis.Bree and Orson have marriage problems because Bree has become too focused on her career as a successful cookbook writer and caterer, while Orson was in prison her daughter came back for her son.Perkins, John Pardee, Joey Murphy, David Grossman, and Larry Shaw.Set on Wisteria Lane, a street in the fictional town of Fairview in the fictional Eagle State, Desperate Housewives follows the lives of a group of women as seen through the eyes of their late friend and neighbor who committed suicide in the pilot episode.Desperate Housewives was well received by viewers and critics alike.It won multiple Primetime Emmy, Golden Globe and Screen Actors Guild Awards.
The season mystery revolves around Edie's new husband, Dave Williams (Neal Mc Donough), who is looking for revenge on someone on Wisteria Lane (later revealed to be Mike).
A tornado threatens to destroy everything, and everyone, that the housewives hold dear.
In the closing minute the characters and their story have flashed forward by five years.
The second season premiered on September 25, 2005, and its central mystery is that of new neighbor Betty Applewhite (Alfre Woodard), who moved onto Wisteria Lane in the middle of the night. Throughout the season, Bree tries to cope with being a widow, unknowingly begins dating the man who poisoned her husband, fights alcoholism, and is unable to prevent the gap between her and her son Andrew Van de Kamp (Shawn Pyfrom) from growing to extremes.
She deals with her daughter Danielle's new romance with Matthew Applewhite.